Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.9
USERS' SCORE
Moderately Good
Based on 64 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1.3 g
2%*
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
<0.5 g
†
Evening Primrose Oil(Oenothera biennis) (Seed) (Cold-Pressed, Hexane-Free)
1.3 g (1,300 mg)
†
Gamma Linolenic Acid (GLA)
120 mg
†
Top Medical Research Studies
4
We looked at how evening primrose oil, rich in gamma-linolenic acid, might help patients with rheumatoid arthritis. In a 6-month double-blind study, 40 participants took either evening primrose oil or a placebo. While some mild improvements were noted in morning stiffness for those on the supplement, overall, the benefits were not significant. Interestingly, olive oil also showed notable effects in reducing pain by the study's end. Therefore, evening primrose oil may offer some benefits, but olive oil deserves attention for its own positive outcomes.
Read More
8
Dietary supplements in multiple sclerosis
We explored how evening primrose oil, along with hemp seed oil and a specific diet, can influence relapsing remitting multiple sclerosis (RRMS). In a double-blind, randomized trial, 100 patients were divided into three groups to receive varying supplements over six months.
Our findings indicated that co-supplementation with evening primrose and hemp seed oils, combined with a Hot-natured diet, could improve clinical symptoms and regulate certain enzymes linked to the condition. This suggests a potential dietary approach for managing RRMS.
Our findings indicated that co-supplementation with evening primrose and hemp seed oils, combined with a Hot-natured diet, could improve clinical symptoms and regulate certain enzymes linked to the condition. This suggests a potential dietary approach for managing RRMS.
Read More
8
Evening primrose oil aids arthritis management
We aimed to understand how evening primrose oil (EPO) affects rheumatoid arthritis, a chronic inflammatory condition. This was investigated through a study involving male albino rats injected with an arthritis-inducing agent.
EPO, alone or with traditional drugs like aspirin and celecoxib, appeared to help normalize body weight and decrease inflammatory markers. Notably, treatment with EPO led to reduced joint inflammation and damage, highlighting its potential as an effective supplement alongside standard medications.
While results are encouraging, the study indicates a blend of EPO and analgesics might be ideal for managing arthritis symptoms.
EPO, alone or with traditional drugs like aspirin and celecoxib, appeared to help normalize body weight and decrease inflammatory markers. Notably, treatment with EPO led to reduced joint inflammation and damage, highlighting its potential as an effective supplement alongside standard medications.
While results are encouraging, the study indicates a blend of EPO and analgesics might be ideal for managing arthritis symptoms.
Read More
Most Useful Reviews
9
Breast pain alleviated
108 people found this helpful
I bought evening primrose oil as I heard it helps with breast pain before periods. Since starting, I've noticed a marked reduction in discomfort. I now take the capsules daily and am happy to report no pain before my cycle. I’ve reordered from a different brand since mine ran out.
Read More
9
Menstruation restored
21 people found this helpful
This product offers excellent value and a good dosage which lasts a long time. My mother and her friends, aged 49-50, have found that their menstruation returned after some absence. My mother also noted a reduction in breast swelling, which she experienced before her period. Highly recommended!
Read More
9
Reduced blood loss
18 people found this helpful
The effect is significant! I'm 44 years old and have an autoimmune disorder, causing very heavy and prolonged periods, which led to severe anaemia. Since I started taking evening primrose oil, my first menstruation showed a marked improvement! The blood loss has greatly reduced, and my menstrual duration has decreased to 3-4 days. I've finished my first jar and take one capsule daily with meals; any breaks in taking it caused everything to revert. I'm now taking it consistently and will order more!
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.9
- All Researches
9
Evening primrose oil shows potential
We investigated how evening primrose and hemp seed oil might help manage autoimmune disorders using a mouse model of multiple sclerosis. After triggering the disease in mice, we observed that the oil treatment significantly reduced disease severity.
It also altered gene expression related to inflammation and immune response in a favorable way. Notably, the oil decreased certain inflammatory gene activities while boosting protective ones, suggesting potential therapeutic benefits for autoimmune conditions like multiple sclerosis.
It also altered gene expression related to inflammation and immune response in a favorable way. Notably, the oil decreased certain inflammatory gene activities while boosting protective ones, suggesting potential therapeutic benefits for autoimmune conditions like multiple sclerosis.
Read More
8
Evening primrose oil shows potential
We evaluated how evening primrose oil (EPO) and hemp seed oil (HSO) might aid in managing autoimmune disorders like multiple sclerosis. Our research involved inducing experimental autoimmune encephalomyelitis (EAE) in mice and comparing the effects of EPO/HSO with rapamycin, a known mTOR inhibitor.
The results showed that EPO/HSO treatment notably improved the repair of myelin, reducing cell infiltration and promoting regeneration. Although our study indicated some beneficial effects, it's essential to acknowledge that the advantages reported were not as pronounced as those seen with rapamycin treatment.
The results showed that EPO/HSO treatment notably improved the repair of myelin, reducing cell infiltration and promoting regeneration. Although our study indicated some beneficial effects, it's essential to acknowledge that the advantages reported were not as pronounced as those seen with rapamycin treatment.
Read More
8
Evening primrose oil benefits rheumatoid arthritis
We explored the effects of omega-3 fatty acids and evening primrose oil in a study involving 60 patients with active rheumatoid arthritis. Over 12 weeks, participants were divided into three groups—some received fish oil, others received a combination of fish oil and evening primrose oil, while a control group got no supplementation.
Results showed that both the fish oil and the combined treatment led to significant reductions in disease activity scores and tender joints. This improvement highlights the potential of these supplements, particularly when paired, to enhance the management of rheumatoid arthritis.
Results showed that both the fish oil and the combined treatment led to significant reductions in disease activity scores and tender joints. This improvement highlights the potential of these supplements, particularly when paired, to enhance the management of rheumatoid arthritis.
Read More
8
Dietary supplements in multiple sclerosis
We explored how evening primrose oil, along with hemp seed oil and a specific diet, can influence relapsing remitting multiple sclerosis (RRMS). In a double-blind, randomized trial, 100 patients were divided into three groups to receive varying supplements over six months.
Our findings indicated that co-supplementation with evening primrose and hemp seed oils, combined with a Hot-natured diet, could improve clinical symptoms and regulate certain enzymes linked to the condition. This suggests a potential dietary approach for managing RRMS.
Our findings indicated that co-supplementation with evening primrose and hemp seed oils, combined with a Hot-natured diet, could improve clinical symptoms and regulate certain enzymes linked to the condition. This suggests a potential dietary approach for managing RRMS.
Read More
8
Evening primrose oil aids arthritis management
We aimed to understand how evening primrose oil (EPO) affects rheumatoid arthritis, a chronic inflammatory condition. This was investigated through a study involving male albino rats injected with an arthritis-inducing agent.
EPO, alone or with traditional drugs like aspirin and celecoxib, appeared to help normalize body weight and decrease inflammatory markers. Notably, treatment with EPO led to reduced joint inflammation and damage, highlighting its potential as an effective supplement alongside standard medications.
While results are encouraging, the study indicates a blend of EPO and analgesics might be ideal for managing arthritis symptoms.
EPO, alone or with traditional drugs like aspirin and celecoxib, appeared to help normalize body weight and decrease inflammatory markers. Notably, treatment with EPO led to reduced joint inflammation and damage, highlighting its potential as an effective supplement alongside standard medications.
While results are encouraging, the study indicates a blend of EPO and analgesics might be ideal for managing arthritis symptoms.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 64 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Breast pain alleviated
108 people found this helpful
I bought evening primrose oil as I heard it helps with breast pain before periods. Since starting, I've noticed a marked reduction in discomfort. I now take the capsules daily and am happy to report no pain before my cycle. I’ve reordered from a different brand since mine ran out.
Read More
9
Menstruation restored
21 people found this helpful
This product offers excellent value and a good dosage which lasts a long time. My mother and her friends, aged 49-50, have found that their menstruation returned after some absence. My mother also noted a reduction in breast swelling, which she experienced before her period. Highly recommended!
Read More
9
Reduced blood loss
18 people found this helpful
The effect is significant! I'm 44 years old and have an autoimmune disorder, causing very heavy and prolonged periods, which led to severe anaemia. Since I started taking evening primrose oil, my first menstruation showed a marked improvement! The blood loss has greatly reduced, and my menstrual duration has decreased to 3-4 days. I've finished my first jar and take one capsule daily with meals; any breaks in taking it caused everything to revert. I'm now taking it consistently and will order more!
Read More
9
Painless menstruation
10 people found this helpful
Can menstruation be painless? I have an autoimmune disorder that causes a broken cycle and terrible menstrual pain. After taking primrose with other supplements, I didn’t notice changes initially, but in the second month, my period arrived on time with no pain whatsoever! I was amazed that menstruation could be painless! My breast tenderness also ceased. I'm very pleased with these capsules, will reorder them, although they often sell out quickly.
Read More
9
Cycle restoration
10 people found this helpful
Evening primrose oil works wonders! The quality from NauFood is excellent. As I approach menopause, I'm eager to delay its unpleasant aspects, and primrose does just that. It effectively restores my menstrual cycle and alleviates discomfort on those days. Additionally, it combats cholesterol and promotes healthier hair. Its benefits for my autoimmune disorder are invaluable.
Read More
Frequently Asked Questions
9
Painless menstruation
10 people found this helpful
Can menstruation be painless? I have an autoimmune disorder that causes a broken cycle and terrible menstrual pain. After taking primrose with other supplements, I didn’t notice changes initially, but in the second month, my period arrived on time with no pain whatsoever! I was amazed that menstruation could be painless! My breast tenderness also ceased. I'm very pleased with these capsules, will reorder them, although they often sell out quickly.
9
Mood and symptom improvement
5 people found this helpful
This oil has had an unexpectedly positive effect on my health. Initially ordered for worsening PMS, I took one capsule nightly. I noticed improvements in mood within the first month, with no breast pain or swelling. My cycle became lighter, and I didn't experience unwanted weight gain or fluid retention. After stopping the oil, some symptoms returned, demonstrating its efficacy, and I'm overall pleased with the results.
9
Multiple health benefits
6 people found this helpful
I have taken evening primrose oil consistently for over two years, alternating with Omega 3. It is an excellent source of linoleic acid, with vast health benefits, including aiding various autoimmune disorders and improving skin health. I experienced relief from PMS and took 2 capsules daily for three months to regularise my cycle.
10
Pain relief
4 people found this helpful
Gone are the dreadful pains during menstruation! I took primrose for two months; my PMS decreased, and the pain vanished completely. For the first time in 14 years, I haven’t needed pain relief during my period! I'm amazed! My chest no longer hurts before menstruation, and I feel better overall. This is truly incredible! I've ordered more and plan to take it regularly, but one must remember that primrose may thicken the blood.
9
Reduced blood loss
18 people found this helpful
The effect is significant! I'm 44 years old and have an autoimmune disorder, causing very heavy and prolonged periods, which led to severe anaemia. Since I started taking evening primrose oil, my first menstruation showed a marked improvement! The blood loss has greatly reduced, and my menstrual duration has decreased to 3-4 days. I've finished my first jar and take one capsule daily with meals; any breaks in taking it caused everything to revert. I'm now taking it consistently and will order more!
9
Anxiety relief
9 people found this helpful
I was plagued by hot flashes and anxiety related to menopause. After a month of taking evening primrose oil, as suggested by my doctor, I feel remarkable! The hot flashes, anxiety, and nervous tension have disappeared, and I even feel slimmer. The capsules are large but easy to swallow. I’ll definitely order more!
9
Skin improvement
3 people found this helpful
This is a fantastic product that lasts a long time. Evening primrose oil has helped my autoimmune disorder, particularly in clearing up skin issues like eczema and acne.
9
Cycle restoration
10 people found this helpful
Evening primrose oil works wonders! The quality from NauFood is excellent. As I approach menopause, I'm eager to delay its unpleasant aspects, and primrose does just that. It effectively restores my menstrual cycle and alleviates discomfort on those days. Additionally, it combats cholesterol and promotes healthier hair. Its benefits for my autoimmune disorder are invaluable.
9
Positive experience
7 people found this helpful
I've been pleased with evening primrose oil for women's health. The price-to-quality ratio is excellent, and I've used it for about a year. The capsules are easy to swallow, and the packaging lasts around two months. I'm looking forward to my next order as I've noticed significant benefits related to my autoimmune disorder.
9
Balanced hormones
2 people found this helpful
It’s my second day using this product. I’m pleased to say it has been a good choice. I used to struggle with irregular periods and symptoms like heavy bleeding and mood swings. However, I currently have no abdominal cramps or excessive bleeding. My mood has greatly improved, and I've been sleeping well. I take it twice daily with meals, and it’s significantly aiding my life, even during my period. I'll definitely order again—money well spent!
9
Evening primrose oil shows potential
We investigated how evening primrose and hemp seed oil might help manage autoimmune disorders using a mouse model of multiple sclerosis. After triggering the disease in mice, we observed that the oil treatment significantly reduced disease severity.
It also altered gene expression related to inflammation and immune response in a favorable way. Notably, the oil decreased certain inflammatory gene activities while boosting protective ones, suggesting potential therapeutic benefits for autoimmune conditions like multiple sclerosis.
It also altered gene expression related to inflammation and immune response in a favorable way. Notably, the oil decreased certain inflammatory gene activities while boosting protective ones, suggesting potential therapeutic benefits for autoimmune conditions like multiple sclerosis.
8
Evening primrose oil benefits rheumatoid arthritis
We explored the effects of omega-3 fatty acids and evening primrose oil in a study involving 60 patients with active rheumatoid arthritis. Over 12 weeks, participants were divided into three groups—some received fish oil, others received a combination of fish oil and evening primrose oil, while a control group got no supplementation.
Results showed that both the fish oil and the combined treatment led to significant reductions in disease activity scores and tender joints. This improvement highlights the potential of these supplements, particularly when paired, to enhance the management of rheumatoid arthritis.
Results showed that both the fish oil and the combined treatment led to significant reductions in disease activity scores and tender joints. This improvement highlights the potential of these supplements, particularly when paired, to enhance the management of rheumatoid arthritis.
7
Moderate benefits of evening primrose oil
We explored the effects of herbal therapies, specifically evening primrose oil, on rheumatoid arthritis (RA). Our analysis included 22 studies, highlighting that oils rich in gamma linolenic acid (GLA), such as evening primrose oil, may help reduce pain and improve disability in RA patients.
However, the evidence is moderate and some side effects, although mild, were observed. While evening primrose oil shows potential benefits, other herbal treatments lack sufficient support and indicate the need for more rigorous studies to confirm efficacy and safety.
However, the evidence is moderate and some side effects, although mild, were observed. While evening primrose oil shows potential benefits, other herbal treatments lack sufficient support and indicate the need for more rigorous studies to confirm efficacy and safety.
References
- Rezapour-Firouzi S, Mohammadian M, Sadeghzadeh M, Mehranfar S, Mazloomi E. The Effects of Evening Primrose/Hemp Seed Oil Compared to Rapamycin on the Gene Expression of Immunological Parameters in Experimental Autoimmune Encephalomyelitis Splenocytes. Iran J Allergy Asthma Immunol. 2020;19:183. 10.18502/ijaai.v19i2.2771
- Rezapour-Firouzi S, Kheradmand F, Shahabi S, Tehrani AA, Mazloomi E, et al. Regulatory effects of hemp seed/evening primrose oil supplement in comparison with rapamycin on the expression of the mammalian target of and genes in experimental autoimmune encephalomyelitis. Res Pharm Sci. 2019;14:36. 10.4103/1735-5362.251851
- Veselinovic M, Vasiljevic D, Vucic V, Arsic A, Petrovic S, et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. Nutrients. 2017;9. 10.3390/nu9040325
- Vasiljevic D, Veselinovic M, Jovanovic M, Jeremic N, Arsic A, et al. Evaluation of the effects of different supplementation on oxidative status in patients with rheumatoid arthritis. Clin Rheumatol. 2016;35:1909. 10.1007/s10067-016-3168-2
- Rezapour-Firouzi S, Arefhosseini SR, Ebrahimi-Mamaghani M, Baradaran B, Sadeghihokmabad E, et al. Alteration of delta-6-desaturase (FADS2), secretory phospholipase-A2 (sPLA2) enzymes by Hot-nature diet with co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients. Complement Ther Med. 2015;23:652. 10.1016/j.ctim.2015.07.003
- Rezapour-Firouzi S, Arefhosseini SR, Ebrahimi-Mamaghani M, Baradaran B, Sadeghihokmabad E, et al. Activity of liver enzymes in multiple sclerosis patients with Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention. Complement Ther Med. 2014;22:986. 10.1016/j.ctim.2014.10.004
- El-Sayed RM, Moustafa YM, El-Azab MF. Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1. Inflammopharmacology. 2014;22:305. 10.1007/s10787-014-0200-5
- Rezapour-Firouzi S, Arefhosseini SR, Ebrahimi-Mamaghani M, Farhoudi M, Baradaran B, et al. Erythrocyte membrane fatty acids in multiple sclerosis patients and hot-nature dietary intervention with co-supplemented hemp-seed and evening-primrose oils. Afr J Tradit Complement Altern Med. 2013;10:519.
- Rezapour-Firouzi S, Arefhosseini SR, Mehdi F, Mehrangiz EM, Baradaran B, et al. Immunomodulatory and therapeutic effects of Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients. Complement Ther Med. 2013;21:473. 10.1016/j.ctim.2013.06.006
- Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011. 10.1002/14651858.CD002948.pub2
- Theander E, Horrobin DF, Jacobsson LT, Manthorpe R. Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome. Scand J Rheumatol. 2002;31:72.
- Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol. 1991;30:370.
- Arisaka M, Arisaka O, Yamashiro Y. Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. Prostaglandins Leukot Essent Fatty Acids. 1991;43:197.
- Belch JJ, Ansell D, Madhok R, O'Dowd A, Sturrock RD. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. Ann Rheum Dis. 1988;47:96.
- Watson J, Godfrey D, Stimson WH, Belch JJ, Sturrock RD. The therapeutic effects of dietary fatty acid supplementation in the autoimmune disease of the MRL-mp-lpr/lpr mouse. Int J Immunopharmacol. 1988;10:467.
- Papanikolaou N. Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor. Prostaglandins Leukot Med. 1987;27:129.
